Behcet’s Syndrome

What is Behcet’s Syndrome?

Behcet’s syndrome is associated with different parts which included inflammation of the blood vessels. It is also known as Morbus Behçe or silk road disease. In this condition the mouth ulcers keep coming again and again. Inflammation around the eye pupil is observed which is known as uvea. Behcet’s syndrome is also known as Behcet’s disease. Because of various neurological complications and ruptured vascular aneurysm this condition can be fatal. As this is a systemic disease visceral organs or internal organs are also involved. People in the age group of 20 to 30’s are affected by this disease. This disease is quite common in the Middle East and Asia but very rare in USA.

Signs and Symptoms

The symptoms depend on the body areas which are affected. Many patients complain about abdominal tenderness and discomfort. Some common symptoms are stated below :

Sores in the mouth and sex organs 

Inflammatory eye disease 

Painful oral mucocutaneous ulcerations

Painful eyes, and decreased visual acuity

Conjuctival redness and hypopyon,

Swelling in the parts of the eye, 

Joint stiffness, swelling and pain is observed 

Pulmonary artery thrombosis can be observed in patients 

Sometimes lungs are also involved where the condition can be so severe that bleeding in the lungs is caused which can lead to death. Neurological problems can also occur where a person many suffer from memory loss, confusion and seizures. These symptoms appear quite late in this disease. Sometimes serious issues are observed such as, swelling in the digestive system, blindness, meningitis and blood clots.


The causes of Behcet’s syndrome is still not confirmed by the doctors. They are unsure about the causes. However, auto inflammation of the blood vessels is observed. Overactive immune system attacks the body parts where the primary cause is still not known. The change in the immune system is still not discovered.


The symptoms are not permanent and they may come and go which becomes difficult for the doctors to diagnose the disease. After the pathologic examination of the body region that is affected, a diagnosis is discovered. The diagnosis is established on the basis of where the ulcers are developed and how are they. The symptoms need to be studied properly by the physician to understand the disease. Thus on several clinical findings the diagnosis is established.


The treatment depends on the severity of the condition and location of the ulcers as well. The treatment is given to control the symptoms and reduce inflammation. For mouth and genital ulcers, the patients are given Steroid like the cortisone gels, pastes like Kenolog in Orabase and the creams. Colchicine or Colcrys can also treat the ulcers which are recurrent in nature. Non steroidal or anti inflammatory drugs are given to the patients complaining inflammation in joints like oral steroids. Injectable cortisone is also given to those where the inflammation is observed in eye, brain skin or the joints. For treating uveitis, Anti-TNF therapy s is given.

There are many types of medicines that may be used in specific types of autoimmune diseases. While some treatments aim at relieving symptoms like pain and inflammation, others target the disease process. Unfortunately, adding to extreme hazards and medical anxiety, some autoimmune diseases like thyroiditis and diabetes make the manufacture of vital components in the form of hormones conducive to the human body difficult. Relaxingly enough, some agents introduced by the developed medical ventures, like, anti-TNF medications are used in autoimmune arthritis and psoriasis. Apart from medications, there are several lifestyle changes that may be adopted along with the treatment of autoimmune diseases. These include eating a healthy and balanced diet, getting regular physical activity, maintaining a healthy body weight, getting adequate rest, reducing stress, etc.